通用数据模型解决了标准化电子健康记录（EHR）数据的许多挑战，但无法将其集成深度表型所需的资源。开放的生物学和生物医学本体论（OBO）铸造本体论提供了可用于生物学知识的语义计算表示，并能够整合多种生物医学数据。但是，将EHR数据映射到OBO Foundry本体论需要大量的手动策展和域专业知识。我们介绍了一个框架，用于将观察性医学成果合作伙伴关系（OMOP）标准词汇介绍给OBO铸造本体。使用此框架，我们制作了92,367条条件，8,615种药物成分和10,673个测量结果的映射。域专家验证了映射准确性，并且在24家医院进行检查时，映射覆盖了99％的条件和药物成分和68％的测量结果。最后，我们证明OMOP2OBO映射可以帮助系统地识别可能受益于基因检测的未诊断罕见病患者。

全球综合合作对于限制全球温度的升高至关重要，同时继续经济发展，例如减少严重的不平等或实现长期经济增长。与N战略代理进行缓解气候变化的长期合作提出了一个复杂的游戏理论问题。例如，代理商可以谈判并达成气候协议，但是没有中央权力可以执行遵守这些协议。因此，设计谈判和协议框架以促进合作，允许所有代理人达到其个人政策目标并激励长期遵守，这一点至关重要。这是一个跨学科的挑战，要求在机器学习，经济学，气候科学，法律，政策，道德和其他领域进行研究人员之间的合作。特别是，我们认为机器学习是解决该领域复杂性的关键工具。为了促进这项研究，在这里，我们介绍了一个多区域综合评估模型，模拟全球气候和经济，可用于设计和评估不同谈判和协议框架的战略成果。我们还描述了如何使用多代理增强学习来使用水稻N训练理性剂。该框架是全球气候合作的基础，这是一个工作组协作和气候谈判和协议设计的竞争。在这里，我们邀请科学界使用Rice-N，机器学习，经济直觉和其他领域知识来设计和评估其解决方案。更多信息可以在www.ai4climatecoop.org上找到。

自适应实验可以增加当前学生从教学干预的现场实验中获得更好结果的机会。在此类实验中，在收集更多数据时将学生分配到条件变化的可能性，因此可以将学生分配给可能表现更好的干预措施。数字教育环境降低了进行此类适应性实验的障碍，但很少在教育中应用。原因之一可能是研究人员可以访问很少的现实案例研究，这些案例研究说明了在特定情况下这些实验的优势和缺点。我们通过使用Thompson采样算法进行自适应实验来评估学生在学生中提醒的效果，并将其与传统的统一随机实验进行比较。我们将其作为有关如何进行此类实验的案例研究，并提出了有关自适应随机实验可能或多或少有用的条件的一系列开放问题。

机器学习（ML）研究通常集中在模型上，而最突出的数据集已用于日常的ML任务，而不考虑这些数据集对基本问题的广度，困难和忠诚。忽略数据集的基本重要性已引起了重大问题，该问题涉及现实世界中的数据级联以及数据集驱动标准的模型质量饱和，并阻碍了研究的增长。为了解决此问题，我们提出Dataperf，这是用于评估ML数据集和数据集工作算法的基准软件包。我们打算启用“数据棘轮”，其中培训集将有助于评估相同问题的测试集，反之亦然。这种反馈驱动的策略将产生一个良性的循环，该循环将加速以数据为中心的AI。MLCommons协会将维护Dataperf。

我们的目标是在杂乱的家庭笼环境中跟踪和识别小鼠，作为对生物学研究的自动行为识别的前兆。这是一个非常具有挑战性的问题，因为（i）缺乏对每只鼠标的视觉特征，（ii）具有恒定遮挡的场景的紧密范围，使标准的视觉跟踪方法无法使用。然而，每个鼠标位置的粗略估计可从唯一的RFID植入物中获得，因此有可能最佳地将来自（弱）跟踪的信息与关于身份的粗略信息相结合。为了实现我们的目标，我们提出以下关键贡献：（a）将识别问题的制定作为分配问题（使用整数线性编程解决），（b）轨迹和RFID数据之间的亲和力的新概率模型。后者是模型的关键部分，因为它提供了对特定粗糙定位的物体检测的原则性概率处理。我们的方法在该识别问题上实现了77％的准确性，并且能够在隐藏动物时拒绝杂散的检测。

虽然我们注意临床自然语言处理（NLP）的最新进展，但我们可以注意到临床和翻译研究界的一些抵抗，因为透明度，可解释性和可用性有限，采用NLP模型。在这项研究中，我们提出了一种开放的自然语言处理开发框架。我们通过实施NLP算法为国家Covid队列协作（N3C）进行了评估。基于Covid-19相关临床笔记的信息提取的利益，我们的工作包括1）使用Covid-19标志和症状作为用例的开放数据注释过程，2）一个社区驱动的规则集合平台，3）合成文本数据生成工作流程，用于生成信息提取任务的文本而不涉及人为受试者。 Corpora来自来自三个不同机构的文本（Mayo Clinic，肯塔基州大学，明尼苏达大学）。用单个机构（Mayo）规则集进行了金标准注释。这导致了0.876,0.706和0.694的F-Scors分别用于Mayo，Minnesota和肯塔基测试数据集。作为N3C NLP子群体的联盟努力的研究表明，创建联邦NLP算法开发和基准测试平台的可行性，以增强多机构临床NLP研究和采用。虽然我们在这项工作中使用Covid-19作为用例，但我们的框架足以适用于临床NLP的其他兴趣领域。

The recent increase in public and academic interest in preserving biodiversity has led to the growth of the field of conservation technology. This field involves designing and constructing tools that utilize technology to aid in the conservation of wildlife. In this article, we will use case studies to demonstrate the importance of designing conservation tools with human-wildlife interaction in mind and provide a framework for creating successful tools. These case studies include a range of complexities, from simple cat collars to machine learning and game theory methodologies. Our goal is to introduce and inform current and future researchers in the field of conservation technology and provide references for educating the next generation of conservation technologists. Conservation technology not only has the potential to benefit biodiversity but also has broader impacts on fields such as sustainability and environmental protection. By using innovative technologies to address conservation challenges, we can find more effective and efficient solutions to protect and preserve our planet's resources.

A Digital Twin (DT) is a simulation of a physical system that provides information to make decisions that add economic, social or commercial value. The behaviour of a physical system changes over time, a DT must therefore be continually updated with data from the physical systems to reflect its changing behaviour. For resource-constrained systems, updating a DT is non-trivial because of challenges such as on-board learning and the off-board data transfer. This paper presents a framework for updating data-driven DTs of resource-constrained systems geared towards system health monitoring. The proposed solution consists of: (1) an on-board system running a light-weight DT allowing the prioritisation and parsimonious transfer of data generated by the physical system; and (2) off-board robust updating of the DT and detection of anomalous behaviours. Two case studies are considered using a production gas turbine engine system to demonstrate the digital representation accuracy for real-world, time-varying physical systems.

We introduce Argoverse 2 (AV2) - a collection of three datasets for perception and forecasting research in the self-driving domain. The annotated Sensor Dataset contains 1,000 sequences of multimodal data, encompassing high-resolution imagery from seven ring cameras, and two stereo cameras in addition to lidar point clouds, and 6-DOF map-aligned pose. Sequences contain 3D cuboid annotations for 26 object categories, all of which are sufficiently-sampled to support training and evaluation of 3D perception models. The Lidar Dataset contains 20,000 sequences of unlabeled lidar point clouds and map-aligned pose. This dataset is the largest ever collection of lidar sensor data and supports self-supervised learning and the emerging task of point cloud forecasting. Finally, the Motion Forecasting Dataset contains 250,000 scenarios mined for interesting and challenging interactions between the autonomous vehicle and other actors in each local scene. Models are tasked with the prediction of future motion for "scored actors" in each scenario and are provided with track histories that capture object location, heading, velocity, and category. In all three datasets, each scenario contains its own HD Map with 3D lane and crosswalk geometry - sourced from data captured in six distinct cities. We believe these datasets will support new and existing machine learning research problems in ways that existing datasets do not. All datasets are released under the CC BY-NC-SA 4.0 license.

We present a Machine Learning (ML) study case to illustrate the challenges of clinical translation for a real-time AI-empowered echocardiography system with data of ICU patients in LMICs. Such ML case study includes data preparation, curation and labelling from 2D Ultrasound videos of 31 ICU patients in LMICs and model selection, validation and deployment of three thinner neural networks to classify apical four-chamber view. Results of the ML heuristics showed the promising implementation, validation and application of thinner networks to classify 4CV with limited datasets. We conclude this work mentioning the need for (a) datasets to improve diversity of demographics, diseases, and (b) the need of further investigations of thinner models to be run and implemented in low-cost hardware to be clinically translated in the ICU in LMICs. The code and other resources to reproduce this work are available at https://github.com/vital-ultrasound/ai-assisted-echocardiography-for-low-resource-countries.